We’re the first clinic to offer a non-injectable version of this groundbreaking therapy, delivering results as impressive as traditional methods. By combining the precision of SkinPen, the only medical microneedling device proven to reach targeted depths within the dermis, with the regenerative power of polynucleotides, we create transformative outcomes for your skin.
Polynucleotides are garnering increasing attention for their transformative effects at a cellular level. Taking over the skincare world and here’s why:
Polynucleotides are bio stimulators, a compound that stimulates cells to function optimally, thus regenerating tissues. Made from fragments of polynucleotide which mirror human DNA.
Firstly, polynucleotides stimulate fibroblast cells, these cells are a specific type of connective tissue cell that produce the extracellular matrix (ECM) structural proteins. Proteins we all know of…collagen and elastin. Collagen is the most plentiful protein in the body. Referred to as the “scaffolding for the skin” giving the skin its plump youthful appearance. As we age, collagen and elastin decrease significantly leading to saggy skin, fine lines and wrinkles.
Secondly, they function very similarly to wound healing agents, promoting the skin to undergo intensive repair. Effectively reducing scar tissue (including stretch marks) and minimizing texturised skin.
Thus, the benefits from polynucleotides are multifaceted, renowned for promoting skin rejuvenation, restoring skin tone, plumpness, elasticity and improving overall skin texture by thickening the tissues.
Why do they differ from other skin boosters such as dermal fillers and Profhilo?
Other skin boosters and composed of pure hyaluronic acid (HA) whereas polynucleotides, are chains of nucleotides which stimulate the fibroblast cells yielding more intense, lasting results. Think of polynucleotides as the super charged treatment.
D’Arcy-Hall Skin Studio is the first skincare clinic to offer this treatment as a none injectable version yet still yielding the same incredible results if injected. By using SkinPen, the only medical micro-needling device proven to reach targeted depths within the dermis and salmon sperm, transformative results are achieved.
All treatments require an in-depth consultation to devise a bespoke plan. Below is a guide.
Tingling – topical anesthetic applied
Course of three within 2 weeks and homecare kit. Results noticeable after 4 weeks, full effect 3 months, last for up to 12 months. Annual treatment
45 minutes
£300 per treatment, course of three £800, includes homecare kit and complimentary Dermalux after every session
24 hours post peel, skin will feel a little tight and appear slightly flushed, flaking around day 3-5
Restored tone / texture. Plumper, firmer, smoother, rejuvenated skin
Polynucleotides are suitable for most individuals seeking to improve skin texture, reduce wrinkles and achieve a more youthful, rejuvenated appearance.
The results of polynucleotide treatments can last up to 12 months, depending on the individual’s skin condition, ageing process and lifestyle. Maintenance treatments may be recommended to sustain the desired results.
Polynucleotides are typically well-received by most patients but as with any treatment, minor side effects such as redness, swelling may occur. These are typically mild and resolve within a few days. You can expect peeling of the skin between day 3-5 after treatment.
When performed by a trained and experienced professional, polynucleotide treatments are considered very safe.






